ARA-290 – COMPREHENSIVE RESEARCH PEPTIDE FOR INNATE REPAIR RECEPTOR AND TISSUE PROTECTION STUDIES

Scientific Overview of ARA-290

ARA-290 (Cibinetide) is a synthetic peptide derived from the three-dimensional structure of erythropoietin (EPO). Unlike erythropoietin, ARA-290 selectively activates the Innate Repair Receptor (IRR) without stimulating erythropoiesis, making it a valuable research peptide for investigating tissue protection, inflammation, and cellular repair mechanisms. This formulation is provided as a nasal spray for laboratory and research applications.

In in-vitro and in-vivo models, ARA-290 has been investigated for its effects on:

• Innate Repair Receptor (IRR) Activation– evaluation of receptor-mediated signaling involved in tissue protection, cellular repair, and inflammatory modulation (Brines et al., 2008)
• Neuroprotection and Nerve Function– investigation of neuronal repair, nerve regeneration, and protection against experimental injury models (Brines & Cerami, 2012)
• Inflammatory and Tissue Repair Pathways– study of cytokine regulation, cellular recovery, and restoration of tissue homeostasis in experimental systems (Brines et al., 2014)

ARA-290 serves as a key research peptide for exploring tissue protection, inflammatory signaling, and peptide-based repair mechanisms.